Bioidentical Hormone Therapy with Slow-Release Pellets: All Your Questions Answered

Hormonal fluctuations are a common “side effect” of getting older, and the symptoms these fluctuations cause can be very unpleasant. The good news is that hormone replacement therapy (HRT) can help, and slow-release pellets are a convenient way to enjoy the benefits of HRT without a lot of hassle.

At his Manhasset and Forest Hills, New York practices, E. Jacob Simhaee, MD, offers hormone pellets to help women restore normal hormone levels and relieve uncomfortable symptoms. Here, learn the answers to our patients' common questions about HRT pellet therapy so you can decide if it’s a good choice for you.

What are slow-release hormone pellets?

Hormone pellets are tiny cylinders — as tiny as a grain of rice — designed to release a steady stream of hormones to supplement and stabilize your natural hormone levels. Since they release hormones “automatically” over time, pellets can be a convenient, reliable alternative to oral hormones and injections.

How do HRT pellets work?

Hormone pellets use bioidentical hormones chemically identical to your body's hormones. As a result, your body uses bioidentical hormones in the same way as it uses natural hormones.

The pellets are placed under your skin, typically in your hip or buttock area. Each pellet releases hormones for several months, after which a new pellet can be inserted.

When are hormone pellets used?

Bioidentical hormone pellets are used to treat a variety of hormone-related health issues, including:

• Symptoms related to menopause
• Weight gain
• Irritability or moodiness
• Fatigue or low energy
• Acne
• Polycystic ovary syndrome (PCOS) symptoms
• Abnormal periods
• Low libido
• Vaginal dryness and discomfort

Bioidentical hormone pellets can be especially effective in women and men whose natural hormone levels are declining due to age.

What happens during pellet insertion?

Pellet insertion is a simple process that takes just a few moments. First, Dr. Smihaee numbs your skin with a topical numbing agent. Then, the pellet is inserted under your skin through a tiny puncture wound. After insertion, you may have some mild soreness around the wound, a temporary effect that resolves quickly. 

How long do pellets stay effective?

HRT pellets typically last 3-6 months. The duration of their effect can vary based on gender, metabolism, weight, and other factors. Dr. Simhaee uses lab tests to monitor your hormone levels to ensure your treatment remains effective and your hormone levels stay optimized.

What happens during pellet removal?

Bioidentical HRT pellets are designed to dissolve over time, so they don’t need to be removed. When it’s time, a new pellet can simply be inserted without removing the old one.

Will my pellet be visible?

Although bioidentical HRT pellets are inserted just beneath the skin, they’re positioned to be invisible to you or anyone else.

How do pellets compare to other methods of HRT?

Pellets are a preferred method of HRT for many people due to their “set-it-and-forget-it” nature. Once the pellet is in place, they don’t require any interaction on your part to remain effective. They’re also designed to release a steady dose of hormones, eliminating potential “peaks and valleys” that can occur with other HRT methods. Pellet therapy can also be dosed and customized based on your specific needs. 

How can I learn more about HRT pellets?

The best way to learn more about hormone pellets and whether they’re a good choice for your needs and your lifestyle is to schedule a visit with Dr. Simhaee. During your visit, the doctor reviews your medical history, symptoms, and treatment goals and performs blood work to measure your hormone levels to recommend an HRT treatment plan that’s right for you.

To schedule your HRT evaluation, request an appointment online or over the phone with Dr. Simhaee and his team at his Manhasset and Forest Hills, New York, practices today.